A: While it won’t change the fundamental awesomeness of Aquarius, there turn out to be quite a few differences:
1) Card size is changed to the narrower Fluxx-sized cards, and deck size is increased to 100 cards.
2) Triples (cards with one half-panel, and 2 quarter-panels, including both horizontal and vertical halves.
3) Rotate Goals changed (back) to Shuffle Goals.
4) Rules to a new cooperative game, suitable for very young players: Maze Escape!
5) Number of Wild Cards increased from one to two, AND now usable as a Wild Action if so desired.
6) Better Quad randomization.
7) Vertical Aces
For more details on these changes, read Andy’s blog post about them.